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Sildenafil
Sildenafil is a pill designed for men facing difficulties during sex (sexual dysfunction).
Sildenafil is not only applied in pulmonary hypertension (high blood pressure in blood vessels of lungs) treatment sometimes.
Specifically if you have erection problems, sildenafil works by increasing blood flow to your your penis when you experience sexual excitement by a temporary time duration.
For instanced it releases stresses on blood vessels in chest through relaxing procedure .
If you buy sildenafil to combat erectile dysfunction it can also be better known as Viagra, Aronix, Liberize or Nipatra which is the brand names it is sold under by manufacturers.
Even with the pulmonary hypertension treatment Sildenafil drug can be known also as the names Revatio and Grandipam.
The pharmacist can dispense the prescribed medication for you and the medicine is affordable as it is also being sold in most pharmacies. It forms an integral part of the commonly used forms such as standard tablets, chewable tablets and aqua in which you swallow.
How Effective Is Sildenafil?
Sildenafil usually works well for all types of men with difficulties getting or maintaining an erection at any dosage, and the response rate is better for men receiving the highest 100mg dose as compared to those who get 50mg or 25mg.
Sildenafil is one of the leading drugs against erectile dysfunction and its maximum dose has a reputation for being the best among all. Therefore, it won’t be a big surprise that most (if not all) of the men who use this drug can get the desired results.
Your licensed health practitioner may suggest that 50 mg of sildenafil is your initial dose if the ED is just mild or moderate in severity. Sildenafil is usually taken as an oral dose of this dosage, which is usually enough for most men to rectify their erectile dysfunction issues and have a pleasurable sexual life.
In other times, sildenafil can be prescribed in a lower of 25 mg if you experience side effects, or if there is no need for the upper dosage of a 50 mg .
Researchers in clinical trial discovered that 82% of examined subjects with ED have noticeable improvements in erectile hardness after the application of sildenafil at 100 mg dosage.
The same studies established that 63% and 74% of men rated the benefit at 50mg and 25mg of sildenafil, respectively.
In another experiment, men were first put on 50 mg a day and then 100mg daily in the following weeks. One of the results when beginning dosing of the drug was a quick erections improvement. People could have more pleasurable intercourses compared to lower doses of sildenafil.
Another study has proved that also the identified tendency of rising consumption was due to smaller lending rates. 4 consecutive weeks were marked by administration of sildenafil at a dose of 50mg and in the subsequent 4 weeks some patients were given a higher dosage – 100mg.
Despite the initial increase of erection quality and general sexual satisfaction levels on the trial dose of sildenafil, the research participants showed even better results by taking 100 mg of sildenafil that was followed by a significant increase of their sexual satisfaction.
How Sildenafil Works ?
Sildenafil belongs to the group of medications that work by selectively inhibiting the activity of an enzyme called phosphodiesterase type 5 (PDE5). Such drugs impede the activities of phosphodiesterase enzyme that breaks down the muscle-relaxing substances. This means more blood can get to the penis, and hence an erection.
However, sildenafil also has its limitations, since it does not cure ED but merely addresses the symptoms of the disease.
The likelihood of individuals develop adverse reactions to the drug is much higher whenever they take more than the prescribed dosage.
How Do I Use Sildenafil?
Take the sildenafil one hour before planned sexual activity, if you decide to use it for that purpose.
After taking a sildenafil the longest you could last for erections is up to 4 hours- meaning you could get erections that last this long, but their normal period will only be about the same.
One sildenafil tablet in a day is enough and you should avoid second dosage in this period. Avoid sildenafil if you are taking any other drugs for ED by yourself.
How Long Do Sildenafil Tablets Take To Work?
In order a patient could use sildenafil tablets on hours 30-60 for them to be effective.
The time of sildenafil doing its job in your bloodstream reaches a maximum level of 1 hour, however, it may start to show its effect 30 minutes beforehand.
Pharmacist’s tip: Sildenafil films are the best when they are taken on an empty stomach, because they always act more quicker that way.
You can crack a tablet after the meal however this does impact on how the sildenafil citrate is absorbed hence it will take longer to take effect or cheap generic cialis for sale effects will be weaker. Such fat food hampers availability of sildenafil in the circulation primarily and can make the drug less bioavailable in the process.
What May Interact With This Medication?
- Cisapride
- Nitrates like amyl nitrite, isosorbide dinitrate, isosorbide mononitrate, nitroglycerin
- Riociguat
This medication may also interact with the following:
- Antiviral medications for HIV or AIDS
- Bosentan
- Certain medications for benign prostatic hyperplasia (BPH)
- Certain medications for blood pressure
- Certain medications for fungal infections like ketoconazole and itraconazole
- Cimetidine
- Erythromycin
- Rifampin
Who Shouldn’t Take Sildenafil?
Sildenafil may not be safe to take for people with certain medical conditions including:Sildenafil may not be safe to take for people with certain medical conditions including:
- The current state of bad health from heart attack or stroke that happened in the last half a year
- Heart disease
- Age-related macular degeneration (a disorder of eyes).
It may also interact with various other medications, in particular nitrates and amyl nitrite which are both prescribed to heart disease patients with high blood pressure. People who are under treatment with nitrates of any type or for pulmonary hypertension are at contraindication for sildenafil usage.
What Can I Expect To Happen When I Take Sildenafil?
You won’t get an erection simply after taking sildenafil, it is more like an ongoing process. Usually, silodenafil goes into the action in approximately one hour after being taken and it is active for about four hours.
This estimate suggests your erection should be tougher and stay longer than in the past by about four hours, allowing you to plan intercourse if the timing suits you.
Sildenafil, as such, can't substitute or change your sexual desire, you will still need to be sexually aroused.
If you’re thinking about having sex after dinner, a word of note: people who have a large meal just before the active ingredients in sildenafil kick in can expect the effects to be delayed by about an hour as well.
Can Sildenafil Stop Working?
It sounds like an obvious thing to do is to give a test to those ED meds about 6 or 8 times before you delegate your verdict as to what works for you and the medication does.
If however, the after this time you are still not feeling better, inform your doctor your health professional and he/she may then recommend either altering the dosage or testing something else.
In case Sildenafil becomes unworkable for you, make an appointment with your physician for him/her to find the second-line treatment.
What Alternatives Can I Use For Erectile Dysfunction?
Among multiple treatments for erectile dysfunction, erections can be maintained.
If you are having sexual problems, then seek the help of a qualified physician that can diagnose the matter and evaluate your general health condition. First of all, your doctor will talk to you about the main treatment strategy which is for you.
Storage And Handling
Keep your medicine in the original container after labeling it and preferably in a room temperature, dry place (unless you are explicitly told otherwise by your healthcare provider or the pharmacist).
The application of the medication should not be kept in a pillbox since it only intended to be done close to sexual act. Keep them in a place that is safe and away from children and animals. Make sure your treatment team tells you where to return the remaining drug to be disposed of. They would be pleased to help you. To not throw it down the toilet and also do not trash it.
Key Facts
- On an average of 30 to 60 minutes, sildenafil will be effective for an episode of erection dysfunction. The timing is adjustable, you can prescribe it up to 4 hours before your desired sexual activity.
- To have an authentically induced erection, sildenafil is required to be utilized independently. You would flop if you did not sexually excite him.
- The most prevalent ones are nausea, lethargy, indigestion, disequilibrium and disorientation. Well, many remain unchanged or with very light side effects.
- That is why when your doctor sildenafil and you also take nitrates (mostly prescribed for chest pain such As), the use of sildenafil is dangerous. This duo could decrease your blood pressure sharply, creating some health problems for you. If for some reason it is doubtful as to which nitrate you may be taking then the best way would be to ask your doctor or pharmacist.
- You should not drink grapefruit juice with Revatio (sildenafil) if you are being treated with this medicine for pulmonary hypertension. It results in different use of the medication.
Warnings
Do not use sildenafil if you are consuming a nitrate drug to treat the problem of heart related pain or problem, including nitroglycerin, isosorbide dinitrate, and isosorbide mononitrate. Also, do not use sildenafil if you are taking any of the recreational drugs that contain nitrites such as poppers. Interaction with nitrate drugs when you are taking sildenafil medication results in a rapid and severe drop in the blood pressure.
In some cases, even side-effects of other medicines can be aggravated when sildenafil is present. For prescription medication do not forget to mention to doctor all the medications you are using currently, especially riociguat. Do keep away from sildenafil when taking riociguat.
Reach your doctor in order to know the counseling or any medical help if your erection became painful or it lasted longer than 4 hours(four hours). Priapism, which means persistent and painful erection, can cause harm to the penis of a person who experiences this condition.
If you experience any unexpected vision loss, you should cease taking sildenafil and call for an ambulance or visit an emergency room.
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