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Xbira (Abiraterone)

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$553 - $1645

Xbira (Abiraterone) is a medication used to treat advanced prostate cancer, particularly metastatic castration-resistant prostate cancer (mCRPC). It works by inhibiting the CYP17 enzyme, which is involved in androgen production, thereby lowering testosterone levels and slowing the growth of prostate cancer cells.

Xbira is often prescribed in combination with prednisone to improve its effectiveness and manage side effects. It is typically taken as an oral tablet.

 

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USA, UK, Europe, Australia, South Africa and other
PACK SIZE PRICE QTY ADD TO CART
120 Tablet/s
$553
($4.61/Tablet/s)
240 Tablet/s
$1100
($4.58/Tablet/s)
360 Tablet/s
$1645
($4.57/Tablet/s)
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Xbira (Abiraterone) is a medication primarily used for the treatment of advanced prostate cancer, especially metastatic castration-resistant prostate cancer (mCRPC), which is a form of prostate cancer that continues to develop notwithstanding low testosterone levels from clinical or careful mutilation. Xbira contains abiraterone acetate, a potent inhibitor of the enzyme CYP17 (cytochrome P450 17A1), which plays a key role in the production of androgens, including testosterone. By inhibiting this enzyme, Xbira significantly reduces androgen levels, helping to slow the growth of prostate cancer cells that rely on testosterone for proliferation.

How Xbira Works: Xbira’s active ingredient, abiraterone acetate, targets and inhibits CYP17, which is involved in the production of androgens in the adrenal glands, testes, and even the prostate cancer cells themselves. By lowering testosterone levels, Xbira reduces the stimulation of prostate cancer cells, slowing their growth and potentially leading to the shrinkage of tumors. This makes it particularly effective in treating prostate cancers that no longer respond to traditional hormone therapies.

Uses:

  • Metastatic Castration-Resistant Prostate Cancer (mCRPC): Xbira is typically prescribed for patients whose prostate cancer continues to grow despite having undergone treatment to lower testosterone levels through surgery or medication.
  • Metastatic High-Risk Castration-Sensitive Prostate Cancer (mHSPC): In some cases, it is used in combination with prednisone to improve treatment outcomes in metastatic prostate cancer before it becomes castration-resistant.

Measurement and Organization: Xbira is taken as an oral tablet, generally one time each day.The standard recommended dose is 1000 mg per day (typically taken as four 250 mg tablets) on an empty stomach. It must be taken at least 2 hours after a meal and no food should be consumed for 1 hour after taking the medication. Xbira is often given in combination with prednisone, which helps manage potential side effects such as fluid retention, high blood pressure, and low potassium levels.

Common Side Effects:

  • Fatigue
  • Joint pain and muscle discomfort
  • High blood pressure (hypertension)
  • Fluid retention and swelling
  • Low potassium levels (hypokalemia)
  • Hot flashes
  • Diarrhea
  • Loss of appetite

Serious Side Effects:

  • Liver toxicity (which requires regular monitoring of liver function)
  • Adrenal deficiency (when the adrenal organs don't create an adequate number of chemicals)
  • Increased risk of heart problems, including heart attacks
  • Severe fluid retention
  • Severe high blood pressure

Precautions:

  • Pregnancy and Breastfeeding: Xbira is not recommended for use in women, particularly during pregnancy, as it may harm a developing fetus. Women should avoid becoming pregnant while taking Xbira and for some time after the last dose.
  • Liver and Kidney Function: Xbira should be used cautiously in individuals with liver or kidney dysfunction. Liver capability ought to be checked consistently during treatment.
  • Drug Interactions: Certain medications, particularly those affecting liver enzymes (like CYP3A4 inhibitors or inducers), may interact with Xbira and affect its efficacy and safety.
  • Smoking: Smoking can decrease the effectiveness of Xbira, so patients are advised to avoid smoking during treatment.

Conclusion: Xbira is a critical part of advanced prostate cancer treatment, offering significant benefits for patients with castration-resistant forms of the disease. When used alongside other medications like prednisone, Xbira helps manage symptoms and slow cancer progression. However, it requires careful monitoring for side effects, particularly liver function and blood pressure. Patients should follow their healthcare provider’s instructions closely to ensure the best possible outcomes.

Active Ingredient

Manufacturer

Cipla Limited

Delivery Time

7 - 14 Days

SKU:

Question 1
What is Xbira (Abiraterone)?

Xbira (Abiraterone) is a medication used primarily for the treatment of advanced prostate cancer, especially metastatic castration-resistant prostate cancer (mCRPC). It works by inhibiting the CYP17 enzyme, which plays a crucial role in the production of androgens like testosterone. By reducing androgen levels, it helps slow the growth and spread of prostate cancer cells.


Question 2
How does Xbira work?

Xbira contains abiraterone acetate, which targets and inhibits the enzyme CYP17. This enzyme is essential for androgen production in the adrenal glands, testes, and even prostate cancer cells. By blocking androgen production, Xbira reduces the stimulation of prostate cancer cells, helping to slow their growth and potentially shrink tumors.


Question 3
What is the recommended dosage of Xbira?

The recommended dosage of Xbira is 1000 mg per day, typically taken as four 250 mg tablets, on an empty stomach. It should be taken at least two hours after a meal, and no food should be consumed for one hour after taking the medication.


Question 4
What types of prostate cancer is Xbira used to treat?

Xbira is mainly used to treat metastatic castration-resistant prostate cancer (mCRPC), a form of prostate cancer that continues to grow despite reduced testosterone levels. It may also be used for metastatic high-risk castration-sensitive prostate cancer (mHSPC) in combination with prednisone.


Question 5
How should Xbira be taken?

Xbira should be taken orally as prescribed, typically once a day. It is essential to take it on an empty stomach (at least 2 hours after a meal) and avoid eating for 1 hour after taking the medication.


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